What is the Best Way to Disinfect a Toothbrush?

No matter your health status or germ avoidance methods, regularly disinfecting your toothbrush can help keep it germ-free and fresh. Doing this helps kill off germs that build up on the bristles and handle.

Sanitizing your toothbrush has several methods at your disposal, from running it through the dishwasher and soaking it in mouthwash or an effervescent denture cleaner, to using common kitchen ingredients as effective methods.

Hydrogen Peroxide

Hydrogen peroxide offers an easy, economical, and effective method of sterilizing a toothbrush. Simply pour fresh three-percent concentration hydrogen peroxide into a small cup, submerge your toothbrush into it for up to 30 seconds before rinsing thoroughly with clean tap water and drying upright so bristles don’t come into contact. Always use a fresh cup each time as this prevents cross contamination from bacteria in previous cups used.

Use a bleach and water solution to effectively sanitize your toothbrush. Create the solution daily, submerging the head of the toothbrush into it for at least six minutes and rinsing thoroughly afterwards with clean water before storing upright for optimal storage conditions.

Rubbing alcohol, commonly used to clean kitchen sponges, can also be used to sanitize toothbrushes. Simply rinse off your brush first to clear away trapped particles before submerging it for around 30 seconds in isopropyl/rubbing alcohol before rinsing out before repeating this step again.

UV-C toothbrush sanitizers use germicidal short wavelength ultraviolet light to kill bacteria and viruses on surfaces, including toothbrushes. While not recommended by the CDC as it can damage bristles, one study did show its efficacy against Strep germs; use according to manufacturer instructions.


Your antibacterial mouthwash can also help sanitize your toothbrush! Fill a small cup with 3% hydrogen peroxide and place your bristle-down toothbrush in it until brushing again, then rinse, let dry and store upright into its holder to protect from future germs.

Denture cleaner contains antimicrobial ingredients that will kill any harmful bacteria on the surfaces of your teeth and gums, making this an easy and effective way to sanitize your toothbrush. Be sure to use special denture cleaner meant for toothbrushes instead of regular mouthwash, and to rinse your brush completely afterwards so as not to damage its bristles.

After each use, rinse your toothbrush after each use and replace it every three months, or sooner if someone in your family is sick with COVID-19 or its bristles appear worn down. Although researchers don’t believe normal bacteria on a toothbrush causes dental issues, it’s still essential that it be regularly cleaned so it dries completely between uses and stored somewhere safe from moisture damage between uses. Running it under hot water helps soften its bristles to release food debris stuck between uses while periodically using one of these sanitization methods can also work well – just remember not placing it inside a microwave or dishwasher as these heat damages could do cause irreparable damage!

Baking Soda

Baking soda is a versatile cleaning ingredient with multiple household uses. Either alone or combined with other products, sodium bicarbonate offers many cleaning advantages including being able to eliminate stubborn stains and foul odors quickly and affordably. Furthermore, its health benefits may also help alleviate heartburn symptoms as well as boost exercise performance.

sodium bicarbonate offers many uses beyond baking, including cleaning dishes and countertops with it, eliminating burned-on food residue in stainless steel pots and pans by adding some to their bottom, cleaning refrigerator shelves and compartments, washing dishes by hand and more.

Mixing one teaspoon of baking soda with water can produce an effective toothpaste, effective at decreasing gum disease and tooth decay by killing bacteria, removing plaque, and whitening teeth. However, keep in mind that using straight baking soda alone has abrasive properties which may wear away enamel over time if used too frequently.

To effectively disinfect a toothbrush, the easiest method is to run hot running water through it before and after each use. This will remove contaminants such as bacteria, germs and saliva, loosen caked-on toothpaste and soften bristles for easier brushing of your teeth. Rinse out the brush when finished before placing in an upright position to air dry completely.

White Vinegar

Your toothbrush brings back bacteria from both you and the bathroom where it was stored, as well as germs from being used over and over again. Therefore, it is vital to regularly disinfect it between uses to kill off any remaining germs or bacteria – various methods exist for doing this including running it through a dishwasher cycle and submerging its head in mouthwash or denture cleaner, while some even freeze or boil their brushes or invest in expensive ultraviolet toothbrush sanitizers.

All these methods may help sanitize your toothbrush, but they may not be as effective as you think. According to a 2019 study, letting too much toothpaste, food debris and germs build up will actually accelerate bristle degradation more than simply brushing with it multiple times daily.

So if you are unsure how best to disinfect your toothbrush, keep this in mind: Regular cleaning with mild detergent such as dishwashing liquid or baking soda and storing upright so it can dry between brushings is the most effective way. However, hydrogen peroxide or mouthwash may also work; simply ensure to rinse it through before placing upright where it can dry completely between brushes. Using rubbing alcohol might work too, just take caution not to allow too much liquid into it or it might damage its bristles!

Boiling Water

After each time you brush, it is advisable to rinse your toothbrush under hot water in order to eliminate contaminating germs, saliva, toothpaste residue and food debris that has accumulated on its bristles and handles – however bacteria, blood or other microorganisms could still linger; so regular brush cleaning should be practiced in order to maintain optimum oral health.

Boiling water is one of the easiest and simplest ways to sterilize your toothbrush. Simply bring a pan of water to a boil, submerge your brush for three minutes in it and remove with tongs after three minutes have elapsed – any longer may damage or melt its handle and bristles! Once finished, let it air dry afterwards.

Antibacterial mouthwash can also provide a simple yet effective method for sanitizing your toothbrush. Simply pour an inch or so into a cup and allow your brush to soak head down for 15 minutes – giving it both disinfecting benefits as well as adding some fresh flavor! This method ensures the highest standard in sanitation!

Hydrogen peroxide and white vinegar are both readily available and cost-effective home sanitizers you can use to disinfect your toothbrush at home, providing reliable sanitization methods. Ultraviolet light technology has long been utilized to kill bacteria on items such as sponges, kitchen utensils and bathroom surfaces – another reliable and straightforward option to disinfecting your toothbrush.


It should come as no surprise that a dishwasher is also an effective way of disinfecting toothbrushes, killing germs and bacteria while simultaneously cleaning dishes. Simply put your brush into the machine for several minutes while it runs – be careful that some brands might discolor or damage over time though!

Another solution is placing your toothbrush in a cup of boiling water for several minutes; the hot temperature kills bacteria while softening bristles and loosening any trapped toothpaste from bristles. However, keep in mind that too much boiling water could melt plastic handles, so only use this option in emergencies or when you cannot rinse your brush properly afterwards.

Not only should your brush be regularly cleaned and stored correctly, it should also be stored correctly. Placing it in the bathroom sink or on the counter exposes it to germs and food particles; similarly storing it in a medicine cabinet or drawer does. Keeping it upright instead of covered helps avoid cross-contamination while also allowing excess water to run off – further aiding its sanitization! For added sanitization there are UV sanitizers on the market that use ultraviolet rays to kill germs and bacteria.