What is considered a high level of CA 19-9?
A CA19-9 level of >100 U/mL is more likely to indicate the presence of malignant diseases, especially early stage of pancreatic cancer (1). The specificity of CA19-9 level >1,000 U/mL for pancreatic cancer was 99% (2).
Is CEA elevated in pancreatic cancer?
Carcinoembryonic antigen (CEA) is one of the most widely used tumor markers and is increased in 30%–60% of patients with pancreatic cancer. Although carbohydrate antigen 19-9 (CA19-9) is the most important serum biomarker in pancreatic cancer, the diagnostic and prognostic value of CEA is gradually being recognized.
What is a high CEA level for pancreatic cancer?
The CEA level was elevated in 32 (49%) of the 65 patients with pancreatic adenocarcinoma in whom it was measured. The mean CEA level for resectable tumors (33 patients) was 5.8 ng/mL compared with 18.1 ng/mL for unresectable tumors (P = .
What causes high CEA levels?
The most frequent cancer which causes an increased CEA is cancer of the colon and rectum. Benign conditions which can elevate CEA include smoking, infections, inflammatory bowel disease, pancreatitis, cirrhosis of the liver, and some benign tumors in the same organs in which an elevated CEA level indicates cancer.
What is normal CEA level?
Normal Results The normal range is 0 to 2.5 ng/mL (0 to 2.5 µg/L). In smokers, slightly higher values may be considered normal (0 to 5 ng/mL, or 0 to 5 µg/L).
Can CA 19-9 be elevated for no reason?
If you do not have cancer and your results show a higher than normal level of CA 19-9, it may be a sign of one of the following noncancerous disorders: Pancreatitis, a noncancerous swelling of the pancreas. Gallstones. Bile duct blockage.
What is the difference between CEA and CA 19-9?
Stemmler, J., Stieber, P., Szymala, A.M., et al. Are serial CA 19-9 kinetics helpful in predicting survival in patients with advanced or metastatic pancreatic cancer treated with gemcitabine and cisplatin? (2003) Onkologie 26: 462-467. 10. Duffy, M.J. CA 19-9 as a marker for gastrointestinal cancers: a review.
What level of CA 19-9 indicates cancer?
Conditions other than cancer can cause higher levels. Here is what your results may mean: If your CA 19-9 is less than 37 U/mL, you may not have cancer. If your CA 19-9 is above 37 U/mL, you may have cancer of the pancreas, liver, gallbladder, lung, colon, or stomach.
How accurate is CA 19-9?
Overall, an elevated serum CA 19-9 level has a sensitivity of 79–81% and a specificity of 82–90% for diagnosing pancreatic cancer in symptomatic patients.
What is the normal range for CA 19-9 blood test?
The normal range of CA 19-9 is between 0 and 37 U/mL (units/milliliter), but people with pancreatic cancer often have higher levels. Not every pancreatic cancer will cause elevated levels of CA 19-9, and some non-cancerous conditions (like pancreatitis and jaundice) can cause high levels of CA 19-9.
How does the CA 19-9 blood test work?
This test measures the amount of a protein called CA 19-9 (cancer antigen 19-9) in the blood. CA 19-9 is a type of tumor marker. Tumor markers are substances made by cancer cells or by normal cells in response to cancer in the body. Healthy people can have small amounts of CA 19-9 in their blood.
CEA is a glycoprotein (sugar protein) present in embryonic tissues and in extracts from normal colonic washings. CA 19-9 is a modified blood group antigen (Lewis (a)). Neither test should be used as a cancer screening test of asymptomatic individuals.
What does carbohydrate antigen ( CA ) 19-9 stand for?
Carbohydrate antigen (CA) 19-9 is a type of antigen released by pancreatic cancer cells. It can also be referred to as a tumor marker. The CA 19-9 Radioimmunoassay (RIA) is a blood test that measures the CA 19-9 level in the blood.
What does CA 19-9 mean for pancreatic cancer?
What Do the CA 19-9 Results Mean? The normal CA 19-9 range in a healthy person is 0-37 units per milliliter. CA 19-9 levels can be higher in patients with pancreatic cancer. Rising CA 19-9 values mean the tumor is growing. If the values stay the same, the disease may be stable.