Auberger Blood Group Polymorphism

Auberger blood group polymorphism is a genetic variant that varies the composition of the antigens of blood groups. It is encoded by the gene BCAM and involves a single rs1135062 allele (A) or a polymorphic change (G). People with this polymorphism are known to have an elevated risk of developing hemophilia A.

The blood group antigens are located on the first N-terminal domain. They are identified by a particular antibody called anti-Lub. The other anti-Lub antibody reacted with transfectants expressing complete cDNA. The Lua and Aub antibodies did not react with transfectants expressing the glycoprotein.

This blood group is rare. The Lu blood group antigen is located on the membrane of the red cell. It is also present on para-Lutheran blood. A person who has a para-Lutheran blood group polymorphism may have a lower level of this blood group.

The two most common types of auberger blood group are au a and b. These two have minor clinical implications in transfusion medicine, but they have a major role in sickle cell disease, also known as PV. There are other blood group types that may cause disease, but they are less common than the two.

Lutheran blood groups contain 18 antigen characters. The para-Lub blood group is caused by homozygosity of an inactive LU gene. This gene is not controlled by the Lutheran locus, but has been associated with Lutheran blood groups.

ISBT has a blood group terminology committee that monitors the use of blood group terminology. They have recently redefined the blood group terminology. They have also devised a collection for the antigens that do not have a system. The committee also recommends the use of ISBT terminology in both traditional and alternative formats.

The blood group antigens are grouped into four classes. Blood group systems are composed of one or more antigens controlled at one gene locus, blood group systems are composed of two or more closely related homologous genes, and blood group collections are grouped into collections. The 700 series contain antigens with low incidence, while the 901 series contain those with high incidence.